Introduction
The Calvert formula lets oncologists dose carboplatin to a target area-under-curve exposure rather than body-surface area, adjusting automatically for the patient's kidney function (GFR).
How to use the Carboplatin AUC Dose Calculator
- Enter the target AUC as prescribed by the oncology protocol.
- Enter the patient's measured or estimated GFR in mL/min.
- Click Calculate to see the total carboplatin dose in mg.
Formula and Calculation Method
Visual breakdown
Why use this calculator
Because carboplatin clearance tracks renal function closely, AUC-based dosing reduces both under- and over-exposure compared with flat or BSA-based dosing. This calculator also charts how the dose shifts across a realistic GFR range.
FAQs
Is GFR the same as creatinine clearance here?
Many protocols use an estimated GFR (e.g. Cockcroft-Gault, capped at 125 mL/min) — always follow the local protocol's preferred method.
What AUC values are typical?
Common targets range from AUC 4 to 6, depending on whether carboplatin is combined with other agents.
Does this calculator cap the GFR?
No, it uses the value entered directly — apply any protocol-specific GFR cap before entering it.